Members in the News -  2007

Nancy Briefs changes SmoothShapes to Eleme' Medical

Nancy Briefs changed the name of her company from SmoothShapes to Eleme' Medical, Inc.  The new name reflects the evolution of the company from product development to broad commercialization and the intent to become a major company in the $4.5 B body shaping market.
 
To support this intention Nancy hired two senior executives from the aesthetic laser industry, William McGrail from Candela and Peter D'Errico from Aesthera, and she closed on $7.5 m venture lending facility to complement the $15m Series B she closed seven months ago.
 
The company's first product, SmoothShapes 100, has proven in objective scientific studies to reduce cellulite by 81%.  The product is based on the pioneering technology, Photomology(TM).
 
Congratulations to Nancy.  This is a bold move to build a standalone aesthetics company in the global market.  We know that you can do it!

Mark Leuchtenberger, CEO of Targanta Therapeutics, filed for a $92.6 million IPO at $12–$14 per share. The company has said that in early 2008 it would make the FDA submission for oritavancin, an antibiotic for the treatment of certain skin infections. The filing is reported in Mass High Tech.

Congratulations to Mark and his team for achieving this milestone.


Ron Ranauro, CEO of GenomeQuest, closed on a $4M Series B round of financing. This round was led by Mosaic Ventures and included previous backers Cross Atlantic Partners, Milestone Venture Partners and Paris-based Societe Generale Asset Management.

GenomeQuest developed a Web-based search tool to help scientists and patent attorneys track down the widely scattered data on genetic mapping. Biogen Idec is one of more than 100 customers using GenomeQuest's tools.

The news was reported in MHT, Sept. 21.

Congratulations to our fellow CEO Roundtable member and his team.


Walter Ogier, CEO of Arbios Systems, reported completion of a successful feasibility clinical trial for the SEPTET™ Liver Assist Device. This medical device filters blood to help damaged livers continue to function. In the trial, 79% of patients with chronic liver failure met the primary clinical effectiveness endpoint. Many of them responded within five hours of initial treatment.
 
The results strongly support expanded trials. SEPTET is intended to be a bridge technology for patients who are waiting for liver transplants. 
 
The full results were published as part of the 9th International Symposium on Albumin Dialysis in Liver Disease (ISAD).  For more information, see www.arbios.com.
 
Improving quality of life and giving hope to critically ill patients have their rewards.  Congratulations to Walter and his team.

Jeff Wager, CEO of Artisan Pharma, announced that his company is starting a Phase 2b trial for ART-123, a treatment for disseminated intravascular coagulation (DIC) in sepsis patients.  The drug will be trialed in 800 patients in North America, Europe, New Zealand, India, and Argentina.  See www.artisanpharma.net

Congratulations to Jeff and his team on reaching this milestone.


Anika Therapeutics just received FDA approval for its wrinkle filler, Elevess.  Anika already markets this injectable treatment for skin wrinkles in Europe through Galderma Pharma.

Chuck Sherwood, CEO of Anika, is a member of CEO Roundtable.  Anika is a public company.


OmniSonics
OmniSonics Medical Technologies in Wilmington, Mass has closed on the first $10m of its Series D round of financing, according to an article in MHT on July 20.  Prism Venture and New England Partners are the lead investors.
Rich Ganz is the CEO of OmniSonics and a member of CEO Roundtable.
 
OmniSonics is focused on medical devices to treat vascular disease.  Its OmniWave System uses a catheter to deliver acoustic energy via a wire to clear hardened arteries and break up clots.  See www.omnisonics.com.
 
Congratulations to Rich and his team as they continue to build the company.

Mercia Tapping and her company, AllergyBuyersClub.com, continue to climb the Boston Business Journal's list of Largest Woman-Owned  Companies.  This year the company is listed as #13, moving up from #15.
 
Mercia has been a member of CEO Roundtable since she started her company with a vision and a credit card in the basement of her home.  We celebrate her continued success.
 
The company selects, tests and sells healthy home products directly to consumers. See www.AllergyBuyersClub.com

Scott Gillis, the CEO of Nucryst Pharmaceuticals, a public company, has been elected to the board of Mass Biotech Council.  Scott joins fellow CEO Roundtable members Mike Webb, CEO of Ascent Therapeutics and Chair of MBC and Mark Leuchtenberger, CEO of Targanta Therapeutics and Vice Chair of MBC.

Also joining the expanded Board of MBC is Errol De Souza, CEO of Archemix Corp., and Frank Thomas , CEO of Critical Therapeutics.

MBC expanded its board following an announcement by Gov. Deval Patrick that  $1billion in state funding is to be provided for the growth of the life sciences industry.
 

Member in the News: Sarah Fuller does it again!

Sarah Fuller, founder and President of Decision Resources Inc. of Waltham announced that a majority share of the company has been sold to Providence Equity Partners.  This is the second time that a private equity firm has bought a majority share of the company.  Sarah will again continue as President and minority share holder.
 
The additional funds will be used to continue the growth of DRI through acquisitions and internal developments.
 
The news is reported in today's on line issue of Mass High Tech.
 
"Decision Resources is a privately held provider of research and advisory services to the pharmaceutical and health care industries. It also owns research firms HealthLeaders-InterStudy, focused on the managed care industry, and Millennium Research Group, which provides market intelligence on the medical device industry".
 
Sarah Fuller has been a member of CEO Roundtable for many years.  We can remember when ...
 
Sarah was our CEO of the Year in 2006 for the exemplary manner she demonstrated in the careful and principled way she took in a majority partner the first time and integrated the several new companies into DRI. 
 
Congratulations to Sarah Fuller.  We couldn't be happier for her or prouder of her accomplishments.

Walter Ogier, CEO of Arbios Systems, has reported that his company closed on $4.8m in a private stock offering.  The funding was led by MicroCapital and included existing investor, Bristol Investment. The company trades on the over-the-counter market under the symbol "ABOS".
Arbios Systems is the developer of artifical liver systems SEPET Liver Assist Device and HepatAssist Cell-Based Liver Support System.  The new funds will be used for product registration of the SEPET system in Europe and for clinical trials in the United States.
 
Walter is a member of CEO Roundtable.

David Chen, Founder and CEO of NextWorth, Inc., is featured in an article on his company in Mass High Tech (April 3, pg 9).  NextWorth's business model has evolved from the time David founded the company while a student at Babson College but the vision of helping buyers of consumer electronics maximize the value of their investment by providing an economic incentive to recycle old products as they upgrade to newer models is still the same. The company has narrowed its focus to iPods and broadened its sourcing to large consumer electronic stores. These stores accept older iPods as trade-ins on new models and NextWorth refurbishes them and sells them, primarily on the internet all around the world. NextWorth just completed another round of funding to expand its operations.

David Chen is a member of the CEO Roundtable's high tech peer group.


Todd Hoffman's company, Collegia, is included in an article in the The Wall Street Journal about how Philadelphia is aggressively marketing itself to college students.  Collegia works with public-private partnerships to market a whole region to new college students. The Philadelphia program is called "Campus Philly" and it promotes the 84 colleges in the Philadelphia area as well as the city and its industry.  In addition to promoting Philadelphia to new college students it also works hard to retain the college graduates from the 84 campuses to work in the area and help attract more new students.
Collegia is doing this type of regional marketing in several midsize cities across the country, including Pittsburgh and Cleveland, but it started by promoting Boston in the same way -- with results that Todd is very proud of and many of us are thankful for.  But he warns that Boston is now complacent and lacks the urgency that helped it achieve its current status. 
 
 
Congratulations to Todd and his team for this well-deserved recognition in The Wall Street Journal.
 

Ron Ranauro announced that he has changed the name of his company to GenomeQuest to more accurately reflect it's long-term mission of providing comprehensive, easy access to gene sequence and related information to improve the quality of life. The company was formerly named Gene-IT.

GenomeQuest is a sequence search solution that enables biologists to evaluate novel gene sequences and allows IP lawyers to evaluate freedom-to-operate, patentability, and competitive landscape features for the same sequences. The solution uniquely combines easy-to-use sequence search and analytics with public and proprietary sequence content, including the industry's largest and most complete indexed archive of more than 40 million patented sequences.

You can learn more about Ron's company at its new Web site: www.genomequest.com

Ron is a member of one of the CEO Roundtables for biotech/pharma companies. The members support this name change!

Nancy Briefs is featured in the Boston Globe, Thursday March 25, in a long story about her new company SmoothShapes, Inc.

The company's first product, SmoothShapes 100, has been proven effective in clinical trials in substantially reducing cellulite in women's legs, hips and buttocks. It uses a patented process of infrared lasers to melt the cellulite fat and automated massage to channel the fluid toward the lymphatic meridians which act as the body's natural drainage network. The product was approved for distribution in the United States last July.

Nancy is quoted as saying, "Women want something that works and are willing to pay."

The SmoothShapes machines will be manufactured by a Welsh company, Chromogenex, Ltd., that will also distribute the product in the European Union.

Nancy Briefs is a member of CEO Roundtable.

Peter Savas, chairman of Boston Life Sciences, announced that Robert Langer, a well-known MIT professor and prolific inventor, has been named chairman of the new science and technology committee of the company. 
 
Other members of the company's new committee include Henry Brem of Johns Hopkins and Gary Frashier of Management Associates.
 
The three also serve as independent members of the company's board of directors.
 
Boston Life Sciences develops diagnostics and therapeutic products for disorders of the central nervous system.
 
The story was reported in Mass High Tech on March 23.
 
Peter is a member of CEO Roundtable®.

Nancy Briefs, CEO of SmoothShapes, announced that the company has completed "Series B" financing of $15m from Three Arch Partners.  The funds will be used to support the worldwide launch of the company's first product, SmoothShapes(R) 100 System.  The product FDA-cleared to treat cellulite.  It uses lasers at predetermined wave lengths in the visible and infrared spectrums with vacuum massage to effect the treatment of cellulite.
 
Nancy Briefs said, "We take great pride in the fact that our claims about SmoothShapes 100 are based exclusively on the results obtained in a rigorous, independent clinical study of the System."  The study concluded that 81% of the patients experienced "significant volumetric reduction in subcutaneous fat."  The SmoothSahpes 100 System can smooth out bumps and decease the circumference of a women's thighs, making them feel firmer and smoother.
 
Targeted markets for the SmoothShapes 100 System will include not only traditional practitioners of aesthetic procedures -- plastic surgeons and dermatologists -- but also non-traditional practitioners, such as ON/GYN and primary care specialists, as well medi-spas, aseptic clinics and health clubs. 
 
The story was reported in today's issues of  Mass High Tech and in Medical Device Daily.
 
Nancy is a member of CEO Roundtable.  SmoothShapes is headquartered in Merrimack, NH.
 
Congratulations to Nancy and her team on the successful (and fast) closing on the Series B and the very rapid move to commercialization.

             
Steve Damalas, owner of New England Data Services (NEDS), and Tim Lawlor, owner of RetroFit Technology, partnered to win a contract from Watertown Public Schools for its data systems and network maintenance.  Both Steve and Tim are members of CEO Roundtable.
 
Steve Damalas started NEDS to leverage the investment he had made in internal data systems and make use of the excess space in his company, Electronic Fasteners, in Waltham.  He then invested to build a top class network hosting site. Craig Brenner is the President of NEDS.
 
Tim Lawlor's company, RetroFit, is thirty years old and has been a major state contractor for years. 

Kirtland Poss, CEO of VisEn Medical, announced that his company has begun a multiyear research and development program with Merck & Co. to develop fluorescence imaging agents to image biomarkers.  The program involves the use of imaging agents to measure disease progression in cardiovascular disease.  Other disease targets include oncology and bone. The story is reported in Mass High Tech, March 6.
 
Congratulations to Kirt and his team as they continue to build the commercial strength of VisEn Medical.
 
Kirt is a member of CEO Roundtable.

Mark Leuchtenberger, CEO of Targanta Therapeutics, was in the Boston Globe and Mass High Tech on Friday, February 9.
 
MHT reported that Targanta Therapeutics of Cambridge, closed a $70M third round of financing. Targanta Therapeutics is asking The FDA for approval of its new antibacterial drug, Oritavancin.  The drug is a treatment for complicated skin and skin structure infections that are often acquired in hospitals and are very resistant to other anti-biotics.  The drug has already cleared two Phase 3 clinical trials.  This round of financing was led by Brookside Capital, Skyline Ventures, Radius Ventures and OrbiMed Advisors.
 
The Boston Globe featured Targanta on the front page of its Business section in a story on how new drugs are being developed from microbes discoverd in soil.  The search for new antibiotics has been receiving much more attention as the "superbugs" that resisit known treatments increase.  The Globe story details some of the long journey of this new drug from microbes in the soil of Haiti to the next new thing awaiting FDA approval. 
 
Mark Leuchtenberger is a member of CEO Roundtable.  

Mass High Tech included the photos of six members who attended the CEO Roundtable seminar on the book The Leadership Talk, led by author, Brent Filson last month.  Pictured were Sarah Fuller, President of Decison Resources, Mike Webb, CEO of Ascent Therapeutics (and Chairman of the Mass Biotech Council), Anita Myer, CEO of Boston Neurofeedback, Bonni DiMatteo, President of Atlantic Consulting, Nancy Kolligian, CEO of Distributor Corp. of New England, and Ben Ticho, Executive Director of Big Brothers/Big Sisters of Central Mass. (MHT, Jan 12, page 19)
 
Brent Filson's book The Leadership Talk: The Greatest Leadership Tool, was a National Book Award finalist and was named a Best Book of the Year  by the Bay Area Publishers Association.

Errol DeSouza, CEO of Archemix Corp., announced that his company has signed an agreement with Merck to team up on a multiyear, multitarget program that focuses on aptamer-based technologies to treat cancer. 
 
Aptamers are single-stranded nucleic acids that can be formed into 3-D shapes, allowing them to bind target molecules in a manner similar to that of antibodies.  See www.archemix.com - the story is reported in Mass High Tech, Jan. 18.
 
Congratulations to Errol and his team on this business success.

Peter Savas, Chairman and CEO of Boston Life Sciences, announced that his company has acquired the rights to develop and commercialize Cethrin, a promising Phase II spinal cord injury drug.  BLS bid $35M for this license from BioAxone Therapeutic of Montreal, Canada, according to the story in Mass High Tech, 1/4/07.
 
Boston Life Sciences is focused on diagnostic and therapeutic products for central nervous system disorders.  Cethrin will be a complementary addition to BLS's product line.  It has demonstrated very good trial results in the treatment of acute spinal cord injury.  The FDA has designated Cethrin as an 'Orphan Drug' which could accelerate certain regulatory approvals and gives BLS a seven-year market exclusivity.
 
Read more at www.bostonlifesciences.com.  Boston Life Sciences is a public company.
 
Peter Savas is a member of CEO Roundtable.  Congratulations to Peter and his team for the success they have had in turning around BLS.

 
 
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